Systemische Leichtkettenerkrankung als Komplikation des Plasmozytoms

Autor: M. Grußendorf, R. Waldherr, H.-P. Seelig, E. Ritz
Rok vydání: 2008
Předmět:
Zdroj: DMW - Deutsche Medizinische Wochenschrift. 109:1405-1409
ISSN: 1439-4413
0012-0472
DOI: 10.1055/s-2008-1069386
Popis: An asymptomatic multiple myeloma of the kappa-light chain type was found in a patient with nephrotic syndrome and renal insufficiency. Light microscopy showed nodular glomerulosclerosis of the kidney similar to diabetic glomerulosclerosis. Diabetes mellitus could not be demonstrated. kappa-Light chain deposits could be shown by immunohistology in the mesangium and the glomerular and tubular basal membrane. In addition, massive kappa-light chain deposits in the sinusoidal walls of the liver and at the dermoepidermal junction of the skin and in the corium were found.
Databáze: OpenAIRE