Systemische Leichtkettenerkrankung als Komplikation des Plasmozytoms
Autor: | M. Grußendorf, R. Waldherr, H.-P. Seelig, E. Ritz |
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Rok vydání: | 2008 |
Předmět: | |
Zdroj: | DMW - Deutsche Medizinische Wochenschrift. 109:1405-1409 |
ISSN: | 1439-4413 0012-0472 |
DOI: | 10.1055/s-2008-1069386 |
Popis: | An asymptomatic multiple myeloma of the kappa-light chain type was found in a patient with nephrotic syndrome and renal insufficiency. Light microscopy showed nodular glomerulosclerosis of the kidney similar to diabetic glomerulosclerosis. Diabetes mellitus could not be demonstrated. kappa-Light chain deposits could be shown by immunohistology in the mesangium and the glomerular and tubular basal membrane. In addition, massive kappa-light chain deposits in the sinusoidal walls of the liver and at the dermoepidermal junction of the skin and in the corium were found. |
Databáze: | OpenAIRE |
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