A reversed-phase liquid chromatographic columns for the analysis of single-stranded oligo-DNAs

Autor: Toshikazu Fukui, Hiroyuki Hatano, Hiromasa Imaishi, Keisuke Makino, Hiroaki Ozaki, Tamio Takeuchi
Rok vydání: 1987
Předmět:
Zdroj: Chromatographia. 23:247-253
ISSN: 1612-1112
0009-5893
DOI: 10.1007/bf02311773
Popis: A reversed-phase liquid chromatographic (RPLC) column, with which large oligodeoxynucleotides (oligo-DNAs) can be separated in well-resolved peaks, has been developed. The column contains only specially selected silica bonded with monochlorodimethyloctadecylsilane. The carbon content of the column packing is the predominant factor to achieve good results. With this column several mixtures containing different large oligo-DNAs could be separated with excellent resolution.
Databáze: OpenAIRE