Chronic pharmacologic treatment of experimental hypoxic pulmonary hypertension

Autor: John H.K. Vogel, Daniel Cameron, Gail Jamieson
Rok vydání: 1966
Předmět:
Zdroj: American Heart Journal. 72:50-59
ISSN: 0002-8703
DOI: 10.1016/0002-8703(66)90627-2
Popis: In this study, the effect of chronic pharmacologic treatment of hypoxic pulmonary hypertension was evaluated. The responses to acute pharmacologic treatment were considerably less than the responses to chronic treatment. These results illustrate the feasibility of chronic pharmacologic treatment for the reduction of hypoxic pulmonary hypertension. Furthermore, these studies confirm the importance of vasoconstriction in chronic hypoxic pulmonary hypertension and the rapidity with which pulmonary arterial pressure may decrease when the hypoxic stimulus is blocked or removed.
Databáze: OpenAIRE