Periventricular Leucomalacia and Seizure in Preterm Infants

Autor:	Mahtab Amirheidari, Reza Nafisi Moghadam, Mona Kharraji
Rok vydání:	2017
Předmět:	Pediatrics medicine.medical_specialty Periventricular leukomalacia business.industry Neuropathology medicine.disease Kowsar Pregnancy duration Basal ganglia Medicine White matter abnormalities Radiology Nuclear Medicine and imaging Statistical analysis business Periventricular Leucomalacia
Zdroj:	Iranian Journal of Radiology.
ISSN:	2008-2711 1735-1065
DOI:	10.5812/iranjradiol.48274
Popis:	Background: Prematurity neuropathology can be categorized as: periventricular leukomalacia (PVL), white matter changes, and basal ganglion, cortex and thalamus disorders. These abnormalities may induce seizure in preterm neonate. The aim of this study was to evaluate the association between white matter abnormalities and seizure in 18 months preterm infants with delay Neurodevelopment (ND). Methods: This is an analytical cross-sectional study on 18 months preterm infants with ND delay who were referred to MRI department of Shaheed Sadoughi hospital of Yazd, 2015 - 2016. The information of birth age (weeks), gender, seizure, and PVL on MRI were collected. All statistical analysis was done by SPSS19. Results: Totally 45 infants were studied. About 55.6% were male and 44.6% female. The mean of pregnancy duration was 32.72 - 2.78 weeks. Seizure frequency was 42.2%. The PVL grading was: 28.9% mild, 20% moderate and 4.4% sever. There was a statistically significance between PVL and birth age (week), Also between seizure and PVL. Conclusions: The high light finding of our study was the higher frequency of seizure in infants without PVL. These findings can be explained by the inclusion criteria of our study.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7cc8b2a09ab1418c8fd71802ab9e08d0 https://doi.org/10.5812/iranjradiol.48274 Zobrazit plný text záznamu