A novel one-pot synthesis of oxazolidinones through direct introduction of CO2 into allylamine derivatives

Autor:	Mirco Costa, Chiara Massera, Laura Soldi, Nicola Della Ca
Rok vydání:	2014
Předmět:	chemistry.chemical_classification Allylic rearrangement Base (chemistry) Double bond Organic Chemistry One-pot synthesis Substituent Biochemistry Combinatorial chemistry Catalysis Allylamine Metal chemistry.chemical_compound chemistry visual_art Drug Discovery visual_art.visual_art_medium
Zdroj:	Tetrahedron Letters. 55:1379-1383
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2014.01.029
Popis:	1,3-Oxazolindin-2-one derivatives were obtained for the first time through carboxylative cyclization of allylamines in the absence of any metal or base catalyst. An electron-withdrawing substituent on the allylic double bond is crucial for the reaction success. Allylamines react with CO2 in MeCN/MeOH mixture and in scCO2 giving satisfactory results.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7cafdaf2ab41848d5a02614c253ab734 https://doi.org/10.1016/j.tetlet.2014.01.029 Zobrazit plný text záznamu Full Text from ScienceDirect