454 Mitral regurgitation and in-hospital mortality in patients with heart failure and low flow low gradient aortic stenosis
| Autor: | Germano Junior Ferruzzi, Angela Pamela Peluso, Tiziana Attisano, Serena Migliarino, Francesco Vigorito, Michele Bellino, Giuseppe Iuliano, Angelo Silverio, Gennaro Provenza, Mario Cristiano, Cesare Baldi, Michele Ciccarelli, Gennaro Galasso, Carmine Vecchione, Rodolfo Citro |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | European Heart Journal Supplements. 23 |
| ISSN: | 1554-2815 1520-765X |
| DOI: | 10.1093/eurheartj/suab132.011 |
| Popis: | Aims This study sought to determine the prevalence, clinical impact, and in-hospital outcome of moderate to severe mitral regurgitation (MR) in patients with low-flow, low-gradient aortic stenosis (LFLG-AS) hospitalized for heart failure (HF). Methods and results Patients with aortic valve thickness and aortic velocities >2.5 m/s hospitalized for heart failure in a single referral centre were prospectively enrolled from 2013 to 2021. LFLG-AS was defined as indexed aortic valve area (iAVA) ≤0.6 cm2/m2, mean transaortic gradient Conclusions Moderate to severe MR is frequently detected in patients with LFLG AS and HF. In this peculiar cohort significant MR has a negative impact on outcome and is independently associated with in-hospital mortality. |
| Databáze: | OpenAIRE |
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