Nickel-catalyzed highly regioselective hydrocyanation of aliphatic allenes

Autor:	Xianjie Fang, Ying Ding, Jinguo Long
Rok vydání:	2021
Předmět:	Reaction conditions chemistry.chemical_compound Allylic rearrangement Nickel Chemistry Organic Chemistry Functional group Hydrocyanation Regioselectivity Organic chemistry chemistry.chemical_element Quaternary carbon Catalysis
Zdroj:	Organic Chemistry Frontiers. 8:5852-5857
ISSN:	2052-4129
DOI:	10.1039/d1qo01099a
Popis:	A nickel-catalyzed hydrocyanation of aliphatic allenes with excellent regioselectivity is developed. This protocol features mild reaction conditions and good functional group tolerance, providing an efficient catalytic pathway to access various allylic nitriles containing quaternary carbon centers in a one-step fashion. In addition, preliminarily attempts were made to investigate an asymmetric version of this reaction.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7c921b9a038d0a80c50cb31bb1de5d1b https://doi.org/10.1039/d1qo01099a Zobrazit plný text záznamu