An expeditious and efficient synthesis of symmetrical tris(indolyl)methanes under catalyst-free conditions in fluorinated alcohols

Autor:	Samad Khaksar, Saeed Mohammadzadeh Talesh, Mahnaz Gholizadeh, Seyed Mohammad Vahdat
Rok vydání:	2012
Předmět:	Inorganic Chemistry Solvent Indole test Tris chemistry.chemical_compound Nucleophile Chemistry Organic Chemistry Environmental Chemistry Organic chemistry Physical and Theoretical Chemistry Biochemistry Catalysis
Zdroj:	Journal of Fluorine Chemistry. 136:8-11
ISSN:	0022-1139
DOI:	10.1016/j.jfluchem.2012.01.002
Popis:	Hexafluoro-2-propanol (HFIP) is explored as an effective medium for the synthesis of symmetrical tris(indolyl)methanes through the reaction of indole derivatives with orthoesters at room temperature. The solvent (HFIP) can be readily separated from reaction products and recovered in excellent purity for direct reuse.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7c83a3850e2bb908388403e4dd6721b6 https://doi.org/10.1016/j.jfluchem.2012.01.002 Zobrazit plný text záznamu Full Text from ScienceDirect