ChemInform Abstract: Stereoselective Synthesis of 5-Monoalkyl and 5,5-Dialkylsubstituted Noviose Derivatives

Autor: Michel Klich, Guillaume L’Hermite, Yannick Benedetti, Periers Anne-Marie, Jean-Luc Haesslein, Sylvette Lachaud, Branislav Musicki, Didier Ferroud, Patrick Laurin, Alain Iltis
Rok vydání: 2010
Předmět:
Zdroj: ChemInform. 31
ISSN: 1522-2667
0931-7597
DOI: 10.1002/chin.200016221
Popis: The stereoselective synthesis of 5-monosubstituted and 5,5-dialkylsubstituted noviose derivatives has been achieved starting from l -arabinose. These noviose derivatives could be used as useful building blocks in probing structure–activity relationships (SAR) of coumarin antibiotics that are inhibitors of DNA gyrase.
Databáze: OpenAIRE