ChemInform Abstract: Stereoselective Synthesis of 5-Monoalkyl and 5,5-Dialkylsubstituted Noviose Derivatives
Autor: | Michel Klich, Guillaume L’Hermite, Yannick Benedetti, Periers Anne-Marie, Jean-Luc Haesslein, Sylvette Lachaud, Branislav Musicki, Didier Ferroud, Patrick Laurin, Alain Iltis |
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Rok vydání: | 2010 |
Předmět: | |
Zdroj: | ChemInform. 31 |
ISSN: | 1522-2667 0931-7597 |
DOI: | 10.1002/chin.200016221 |
Popis: | The stereoselective synthesis of 5-monosubstituted and 5,5-dialkylsubstituted noviose derivatives has been achieved starting from l -arabinose. These noviose derivatives could be used as useful building blocks in probing structure–activity relationships (SAR) of coumarin antibiotics that are inhibitors of DNA gyrase. |
Databáze: | OpenAIRE |
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