Abstract P410: Spontaneous Coronary Artery Dissection and Intervention With Percutaneous Coronary Intervention (PCI): A Population Based Study 2016-2019

Autor: Yaser Khalid, Kirti Dasu, Rohan Umrani, Trinava Roy, Neethi Dasu, Bhavana Kadiyala
Rok vydání: 2023
Předmět:
Zdroj: Circulation. 147
ISSN: 1524-4539
0009-7322
DOI: 10.1161/circ.147.suppl_1.p410
Popis: Background: Spontaneous coronary artery dissection (SCAD) remains an important cause of myocardial infarction. A paucity of data exists regarding optimal management of SCAD due to lack of randomized trials comparing medical therapy and revascularization strategies. Methods: Data were extracted from the National Inpatient Sample (NIS) 2016-2019 Database. The NIS was searched for hospitalizations for adult patients with SCAD as principal discharge diagnosis with and without intervention with percutaneous coronary intervention (PCI) as secondary diagnosis using ICD-10 codes. The primary outcome was inpatient mortality. Multivariate logistic and linear regression analysis was used accordingly to adjust for confounders. STATA software was used for analysis. Results: 2,400 patients who had SCAD were divided into those that had PCI versus those who did not-- followed by matching. Majority of the patient population was noted to be females (76.9%) and mean age was a 54.63 years. The adjusted odds ratio (OR) for inpatient mortality for SCAD with PCI intervention showed significantly reduced mortality (OR 0.32, p Conclusion: Previous studies showed that the majority of patients with SCAD except those with high risk should have a conservative revascularization strategy. Our study shows decreased mortality, hospital LOS, and total charges for patients with SCAD who had intervention with PCI. Randomized clinical trials will need to further examine the role of PCI for SCAD in different populations.
Databáze: OpenAIRE