Autor: |
McAvoy, Kathleen, Scobie, Kimberly, Berger, Stefan, Russo, Craig, Guo, Nannan, Decharatanachart, Pakanat, Ramirez, Hugo-Vega, Miake-Lye, Sam, Whalen, Michael, Nelson, Mark, Bergami, Matteo, Bartsch, Dusan, Berninger, Benedikt, Hen, Rene, Sahay, Amar, ilyas, Altamash |
Rok vydání: |
2022 |
Předmět: |
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DOI: |
10.17605/osf.io/6za9m |
Popis: |
The neural circuit mechanisms underlying the integration and functions of adult-born dentate granule cell (DGCs) are poorly understood. Adult-born DGCs are thought to compete with mature DGCs for inputs to integrate. Transient genetic overexpression of a negative regulator of dendritic spines, Kruppel-like factor 9 (Klf9), in mature DGCs enhanced integration of adult-born DGCs and increased NSC activation. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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