Unstrained C–C bond activation and directed fluorination through photocatalytically-generated radical cations

Autor:	Thomas Lectka, Michelle Sheanne Bloom, Qinze Arthur Zhang, Cody Ross Pitts, Desta Doro Bume
Rok vydání:	2015
Předmět:	chemistry.chemical_compound Radical ion 010405 organic chemistry Chemistry Yield (chemistry) Radical fluorination General Chemistry 010402 general chemistry Selectfluor Photochemistry 01 natural sciences 3. Good health 0104 chemical sciences
Zdroj:	Chemical Science. 6:5225-5229
ISSN:	2041-6539 2041-6520
Popis:	Expanding the repertoire of controlled radical fluorination techniques, we present a photosensitized unstrained C–C bond activation/directed monofluorination method using Selectfluor and 9-fluorenone. The reaction is amenable to the opening of multiple 1-acetal-2-aryl substituted rings to yield ω-fluoro carboxylic acids, esters, alcohols, and ketones with relative ease. Initial mechanistic insight suggests radical ion intermediates.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7c4d6fedbb3ee6a57fe5e2471ad52e8c https://doi.org/10.1039/c5sc01973g Zobrazit plný text záznamu