| Popis: |
Objective: To clarify clinical features of sleep disorders in patients with Parkinson‘s disease (PD) and their effect on cognitive function and emotional-personal sphere. Material and methods: The study involved 62 patients with PD (33 men and 29 women) mean age 47.8+7.1 years. The control group consisted of 20 patients without Parkinsonism matching by age and sex. The diagnosis of PD was established by criteria A.Hughes. Patients underwent an extended neuropsychological study with qualitative and quantitative analysis. To determine cognitive disorders, we used neuropsychological tests. Results: 49 patients (79,3%) had sleep disorders. In the structure of sleep disorders: 29 (59.2%) patients had insomnia and 11 (22.4%) patients – parasomnia and 9 (18.4%) hypersomnia. In a control group, numbers were 4.5 times less. The analysis showed that the structure of sleep disorders correlates with the form of PD. So, insomnia is more rapidly met in akinetic-rigid form (55.5%), whereas hypersomnia is presented in mixed form. Patients with insomnia present 35% of predement cognitive impairment and 34% of dementia (66.7% of mild degree dementia and 33.3% moderate dementia severity). Whereas, in patients with hypersomnia 35% of predement cognitive impairment, 60% of dementia (54.6% and 45.4%) were observed. Among patients with permanent drowsiness 32.4% of predement cognitive impairment and 58.4% of dementia (44.8% and 55.2%) were diagnosed. Dementia (65.4%) was observed more in patients with sudden sleep (42,8% and 57.2%). Conclusion: sleep and wakefulness disorders depend not only on the severity of motor symptoms, but also depend on the emotional and cognitive state. |
