Measurement and modeling solubility of bioactive coumarin and its derivatives in supercritical carbon dioxide

Autor:	Ki-Pung Yoo, Hun Yong Shin, Min Jeong Noh, Seong Sik You
Rok vydání:	1997
Předmět:	Boiling point Supercritical carbon dioxide Molar volume Vapor pressure Computational chemistry Chemistry General Chemical Engineering Acentric factor Supercritical fluid extraction Organic chemistry General Chemistry Solubility Supercritical fluid
Zdroj:	Korean Journal of Chemical Engineering. 14:341-346
ISSN:	1975-7220 0256-1115
DOI:	10.1007/bf02707049
Popis:	To design a supercritical fluid extraction process for the separation of bioactive substances from natural products, a quantitative knowledge of phase equilibria between target biosolutes and solvent is necessary. How-ever, mostly no such information is available in literature to date. Thus in the present study, illustratively the solubility of bioactive coumarin and its various derivatives (i.e., hydroxy-, methyl-, and methoxy-derivatives) in supercritical CO2 were measured at 308.15–328.15 K and 10–30 MPa. Also, the pure physical properties such as normal boiling point, critical constants, acentric factor, molar volume and standard vapor pressure for coumarin and its derivatives were estimated. By these estimated information, the measured solubilities were quantitatively correlated by an approximate lattice equation of state proposed recently by the present authors.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7c348cf79b199c902024f2af81e060f5 https://doi.org/10.1007/bf02707049 Zobrazit plný text záznamu Full text from SpringerLink