Proximal conduction block in the pharyngeal-cervical-brachial variant of guillain-barrÉ syndrome
Autor: | Yann Duclos, Guillaume Taieb, Jérôme Franques, Shahram Attarian, Dimitri Renard, Aude-Marie Grapperon, Pierre Labauge, Nobuhiro Yuki |
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Rok vydání: | 2015 |
Předmět: |
Neural Conduction
Pathology medicine.medical_specialty Nerve root Guillain-Barre syndrome Physiology business.industry Stimulation technique medicine.medical_treatment bacterial infections and mycoses medicine.disease Median nerve Pharyngeal muscles Cellular and Molecular Neuroscience Muscle nerve medicine.anatomical_structure Physiology (medical) Anesthesia medicine Plasmapheresis Neurology (clinical) business reproductive and urinary physiology |
Zdroj: | Muscle & Nerve. 52:1102-1106 |
ISSN: | 0148-639X |
Popis: | Introduction: Conduction block (CB) has been included in the Rajabally criteria for axonal Guillain–Barre syndrome (GBS). Because the nerve roots may be affected early in GBS, detection of proximal CB by the triple stimulation technique (TST) can be useful. Methods: We describe TST findings in 2 patients who presented with the pharyngeal–cervical–brachial (PCB) variant of axonal GBS. Results: In the first patient, although conventional nerve conduction studies (NCS) did not fit electrodiagnostic criteria for axonal GBS, the TST detected proximal CB in the median and ulnar nerves. In the second patient, NCS fulfilled criteria for axonal GBS, and the TST detected proximal CB in the median nerve. After plasmapheresis, NCS and TST findings were normalized, suggesting reversible conduction failure rather than demyelinating CB. Conclusion: The TST may be useful for diagnosis of PCB when NCS remain inconclusive. The technique provides additional clues for classifying PCB into the acute nodo-paranodopathies. Muscle Nerve, 2015 |
Databáze: | OpenAIRE |
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