Autor: |
Eleni Chatzidimitriou, Dominika Średnicka-Tober, Juan Wang, Carlo Leifert, Hannah Davis, Gultakin Hasanaliyeva, Per Ole Iversen, Catherine Hadall, Hans-Wolfgang Hoppe, W Nikolaus Kühn-Velten, Chris J. Seal, Steven Rushton, Vanessa Vigar, Nikolaos Volakakis, Marcin Barański, Anthony W. Watson, Leonidas Rempelos, Amelia Magistrali |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
The American Journal of Clinical Nutrition. 115:364-377 |
ISSN: |
0002-9165 |
DOI: |
10.1093/ajcn/nqab308 |
Popis: |
BACKGROUND Observational studies have linked pesticide exposure to various diseases, whereas organic food consumption has been associated with positive health outcomes. Organic farming standards prohibit the use of most pesticides, and organic food consumption may therefore reduce pesticide exposure. OBJECTIVES To determine the effects of diet (Western compared with Mediterranean) and food type (conventional compared with organic) and sex on urinary pesticide residue excretion (UPRE), as well as associations between specific diet components and UPRE. METHODS In this 2-wk, randomized dietary intervention trial, healthy adults were randomly allocated to an intervention (n = 13) or conventional (n = 14) group. Whereas participants in the intervention group consumed a Mediterranean diet (MedDiet) made entirely from organic foods, the conventional group consumed a MedDiet made entirely from conventional foods. Both groups consumed habitual Western diets made from conventional foods before and after the 2-wk intervention period. The primary outcome was UPRE. In addition, we assessed diet composition and pesticide residue profiles in foods eaten. Participants were aware of group assignment, but the study assessors were not. RESULTS During the intervention period, total UPRE was 91% lower with organic (mean 17 μg/d; 95% CI: 15, 19) than with conventional (mean 180 μg/d; 95% CI: 153, 208) food consumption (P |
Databáze: |
OpenAIRE |
Externí odkaz: |
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