A rationally engineered specific near-infrared fluorogenic substrate of human pancreatic lipase for functional imaging and inhibitor screening

Autor: Fan-Bin Hou, Na Zhang, Xu-Dong Hou, Wei Liu, Yu-Fan Fan, Guang-Hao Zhu, Yue Wu, Meng-Ru Sun, Bei Zhao, Guang-Bo Ge, Ping Wang
Rok vydání: 2023
Předmět:
Zdroj: The Analyst. 148:2225-2236
ISSN: 1364-5528
0003-2654
Popis: A novel NIR fluorogenic substrate was rationally designed towards hPL, which can detect endogenous PL in living cells and tissues, and enable visual high-throughput screening of hPL inhibitors.
Databáze: OpenAIRE