The formation of a rearranged product on dehydration of a bicyclic nitrone-hydroxylamine

Autor:	Lord Todd, V.M. Clark, R. F. C. Brown
Rok vydání:	1966
Předmět:	chemistry.chemical_classification Bicyclic molecule Organic Chemistry medicine.disease Biochemistry Chloride Medicinal chemistry Toluene Nitrone chemistry.chemical_compound Hydroxylamine chemistry Drug Discovery Pyridine medicine Organic chemistry Dehydration Triethylamine medicine.drug
Zdroj:	Tetrahedron. 22:15-26
ISSN:	0040-4020
DOI:	10.1016/s0040-4020(01)82165-7
Popis:	Dehydration of the nitrone-hydroxylamine (II) with toluene- p -sulphonyl chloride and triethylamine gives the rearranged product. 2,3,4,5-tetrahydro 5,5-dimethyl 3-oxo-2-(4′,5′,5′-trimethylpyrrolidin-2′ ylidene) pyridine (III). The benzoate of (III) undergoes rearrangement in dilute acid to give the pyrrolo-imidazole (XI).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7c1e41125ef849bde9ef4bb3200f4e7a https://doi.org/10.1016/s0040-4020(01)82165-7 Zobrazit plný text záznamu