Effectiveness of Boiled Cherry Leaf (muntingia calabura L) Toward Ureum Creatinine Serum of Wistar Strain Mice with Acute RenalFailure Model

Autor:	Untung Sudharmono, Perdana Kusumaningrum
Rok vydání:	2019
Předmět:	Creatinine Strain (chemistry) business.industry Renal function Positive control General Medicine chemistry.chemical_compound Animal science chemistry Urea Medicine Gentamicin Analysis of variance Creatinine.serum business medicine.drug
Zdroj:	Abstract Proceedings International Scholars Conference. 7:727-743
ISSN:	2476-9606 2408-3291
DOI:	10.35974/isc.v7i1.2077
Popis:	Renal failure is a clinical condition that is characterized by a decrease in kidney function with an indicator of changes in the levels of urea and creatinine. The purpose of this study is to determine the effectiveness of Boiled Cherry leaf (muntingia calabura L) on the reduction of ureum and creatinine levels. The objects in this study were 30 male Wistar strain rats aged 2-3 months with a weight of 180-200 grams. Rats were randomly grouped into 3 groups: the treatment group, positive control and negative control. The positive treatment and control group was induced gentamicin 0.3 cc IP / day for 7 days. Boiled water from 10 grams of cherry leaves (muntingia calabura) in 200 cc of boiling water to 100 cc was given as much as 3.6 cc orally for 7 days to the treatment group. Data were analyzed with SPSS version 24, One test ANOVA was performed to compare urea and creatinine levels. The results showed that there were significant differences in urea and creatinine levels between the treatment group and the positive control group (p
Databáze:	OpenAIRE
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