Synthesis of α- and β-C-glycosides of N-acetylglucosamine

Autor:	Frank W. Schmidtmann, Darin E. Kizer, Tyler E. Benedum, Glenn J. McGarvey
Rok vydání:	2003
Předmět:	C glycosides Olefin fiber Stereochemistry Organic Chemistry Biochemistry Catalysis Metal Turn (biochemistry) chemistry.chemical_compound chemistry Glucosamine visual_art Drug Discovery visual_art.visual_art_medium N-Acetylglucosamine Organic chemistry Isomerization
Zdroj:	Tetrahedron Letters. 44:3775-3779
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(03)00818-9
Popis:	As part of efforts to make available new classes of bioactive C-glycoconjugates, d -glucosamine has been effectively converted into a series of 2-deoxy-2-amino-C-glycosides. This versatile approach is keyed by a remarkably effective metal catalyzed olefin isomerization of the isomeric C-allyl amino sugars which, in turn, are readily available via radical allylation of d -glucosamine.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7c0d28daef49ff750d3e494699023527 https://doi.org/10.1016/s0040-4039(03)00818-9 Zobrazit plný text záznamu Full Text from ScienceDirect