SU-8 C-MEMS as candidate for long-term implantable pacemaker micro electrodes

Autor:	Jonas Grossenbacher, Juergen Brugger, H. Tevaearai Stahel, Stéphanie Lecaudé, Maurizio R. Gullo
Rok vydání:	2015
Předmět:	Microelectromechanical systems Materials science In vivo Electrode Metal electrodes Electrochemistry Ex vivo Peripheral muscle Biomedical engineering Microfabrication
Zdroj:	2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS).
DOI:	10.1109/transducers.2015.7181061
Popis:	This paper presents the first successful implantation of electrically conductive SU-8 C-MEMS electrodes able to pace muscle tissue in an animal model. The electrochemical characterizations of the ceramic electrodes show comparable values to state of the art platinum (Pt) metal electrodes. The micro-fabricated pacemaker electrodes were successfully tested in vitro (cardiomyocyte), in vivo (rat peripheral muscle) and ex vivo (explanted rat heart) pacing experiments. Short term C-MEMS implantation assays show lower levels of fibrosis compared to conventional electrodes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7bc5b4a6b90aaf855466485d83c86360 https://doi.org/10.1109/transducers.2015.7181061 Zobrazit plný text záznamu