β-Carbolines: synthesis of harmane, harmine alkaloids and their structural analogs by thermolysis of 4-aryl-3-azidopyridines and investigation of their optical properties

Autor:	Anastasiya S. Belousova, Vladislav Yu. Shuvalov, Evgenii V. Arshinov, Valeriya А. Elisheva, Galina P. Sagitullina, Marina А. Vorontsova, Aleksander S. Fisyuk, Sergei А. Chernenko, Larisa V. Glyzdinskaya
Rok vydání:	2020
Předmět:	010405 organic chemistry Aryl Organic Chemistry Thermal decomposition Biological activity 010402 general chemistry 01 natural sciences Combinatorial chemistry Fluorescence 0104 chemical sciences chemistry.chemical_compound Harmine chemistry Drug delivery Harmane DNA
Zdroj:	Chemistry of Heterocyclic Compounds. 56:73-83
ISSN:	1573-8353 0009-3122
DOI:	10.1007/s10593-020-02625-4
Popis:	Interest in β-carbolines is caused by the biological activity of these compounds and the use of their fluorescent properties in the study of their interaction with DNA and other biological targets, as well as with drug delivery vehicles. A new general method for the synthesis of harmane, harmine, and their structural analogs by thermolysis of substituted 4-aryl-3-azidopyridines was developed, and their optical properties were studied.
Databáze:	OpenAIRE
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