Nucleoli and the nucleoli–centromere association are dynamic during normal development and in cancer
| Autor: | Aaron Rodrigues, Kyle L. MacQuarrie, Emma Freeman, Alicia Lin, Alexander B. Willis, Zhaofa Xu, Angel A. Alvarez, Yongchao Ma, Bethany E. Perez White, Daniel R. Foltz, Sui Huang |
|---|---|
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Molecular Biology of the Cell. 34 |
| ISSN: | 1939-4586 1059-1524 |
| Popis: | In this study, the authors show nucleoli and centromeres interact dynamically not only during normal differentiation across a variety of cellular models including myocytes, keratinocytes, and neurons, but in cancer cells as well. Differentiation leads to a decrease in association between centromeres and nucleoli, with cancer cells exhibiting an increased association frequency more typical of proliferative cells. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|