| Autor: |
D.V. Mikhailov, O.V. Kostromina, E.A. Novikova, S.V. Sazonov, S.L. Leontiev |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Journal of Ural Medical Academic Science. 17:187-192 |
| ISSN: |
2073-9125 |
| DOI: |
10.22138/2500-0918-2020-17-2-187-192 |
| Popis: |
Aim. The aim of the study was to determine the presence of peculiarities of the age structure in patients with various surrogate molecular biological subtypes of breast cancer. Materials and research methods. This work analyzes the age-related characteristics of the occurrence of molecular biological subtypes in 499 patients with invasive breast cancer. All cases were divided into 5 molecular biological subtypes based on immunohistochemical studies of hormone receptors, Her2, Ki-67. The average age of the patients was 53.4±0.39 years, the predominant group was patients from 50 to 60 years (37.2% of the total). Research results. In patients under 40 years old, the triple negative subtype prevailed (44.8%). Luminal A subtype prevailed in the groups 51-60 years old (more than 41.4%) and over 60 years old (39.7%). Luminal B (Her2-) subtype was equally found in all age groups. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
