Studies on the Genetic Multiplicity of a Gene in Yeast Cells, I Characteristics of the Induced Mutations by Subcritical Temperature and Ultraviolet Light

Autor:	Yoriaki Matsudaira, Terutoshi Yamasaki, Takashi Ito
Rok vydání:	1962
Předmět:	Locus (genetics) General Medicine Gene mutation Biology Molecular biology Yeast chemistry.chemical_compound chemistry Duplex (building) Genetics Nucleic acid Ultraviolet light Gene DNA
Zdroj:	The Japanese Journal of Genetics. 37:276-283
ISSN:	1880-5787 0021-504X
DOI:	10.1266/jjg.37.276
Popis:	By using subcritical temperature and ultraviolet light as DNA-attacking agents, the duplex nature of ad locus gene mutation in yeast cells was studied at the molecular level. The relative frequencies of whole-colony mutation and fractional-colony (sectored) mutation induced by these two agents are strikingly different: 59% whole, 23% fractional and 18% undefined for subcritical temperature; 14% whole, 72% fractional and 13% undefined for ultraviolet light. The results are interpreted to indicate a genetic multiplicity of two of the genes, based on the assumption that subcritical temperature causes changes by a single event in both strands of a gene-DNA molecule and ultraviolet in one of the two strands. (H.M.G.)
Databáze:	OpenAIRE
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