| Autor: |
Krisztina Wolfard, Toru Tanaka, Noboru Motohashi, Satoru Tani, Hideki Nakashima, Shigemi Terakubo, Hiroshi Sakagami, Kazue Satoh, Joseph Molnár, Masami Kawase, Bhattiprolu Kesava Rao |
| Rok vydání: |
2004 |
| Předmět: |
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| Zdroj: |
Oriental Pharmacy and Experimental Medicine. 4:179-185 |
| ISSN: |
1598-2386 |
| DOI: |
10.3742/opem.2004.4.3.179 |
| Popis: |
The ethanol extract of Indigofera cordifolia was studied for in vivo gastroprotective activity, cytotoxic activity against oral tumor and normal cells, multidrug resistance (MDR) reversal activity, anti-human immunodeficiency virus (HIV) activity and radical scavenging activity. The extract of I. cordifolia showed potent gastric mucosal protective activity against stomach injury induced by HCl/EtOH solution. However, the gastroprotective activity could not be related to the radical mechanism, because the extract weakly scavenged both OH radical and . The extract also showed promising levels of MDR-reversing activity. This study demonstrates the tumor-specific cytotoxic action of the plant extract. However, the extract had no anti-HIV activity. From above results, the study suggests the medicinal importance of I. cordiforia extract. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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