| Autor: |
An Guo Teng, An Jun Liu, Zhen Yuan Zhu, Qi Rong, Wen Hang Wang, Guo Qiang Zheng, Jing Jing Fang, Yu Gang Qi |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
Advanced Materials Research. 716:451-454 |
| ISSN: |
1662-8985 |
| DOI: |
10.4028/www.scientific.net/amr.716.451 |
| Popis: |
The antitumor activity of porcine cartilage polysaccharide was evaluated by vivo animal models. The Ca761 tumor-bearing mice were treated with daily intraperitoneal injections of normal saline (control group) or cartilage polysaccharide (1500, 3000 or 4500mg/kg CPS group) for 14 days. The results demonstrated that CPS could effectively inhibit the tumor growth in Ca761 tumor-bearing mice. The tumor weights of the CPS groups were smaller compared to the control group. While the thymus index, spleen index were higher in the high dose 4500mg/kg CPS group than the control group. These results suggest that CPS might be a strong natural immunomodulator and the antitumor effect of this polysaccharide is associated with its potent immunostimulating effect. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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