Selective Syntheses of Coumarin and Benzofuran Derivatives Using Phenols and α-Methoxy-β-ketoesters

Autor:	Masahiro Egi, Takashi Shigeta, Ryo Miyata, Shigenori Kumazawa
Rok vydání:	2023
Předmět:	Biomaterials Materials Science (miscellaneous) Organic Chemistry Catalysis
Zdroj:	SynOpen. :8-16
ISSN:	2509-9396
DOI:	10.1055/s-0042-1751408
Popis:	Selective syntheses of coumarin and benzofuran derivatives were achieved via HClO4-mediated intermolecular annulation using phenols and α-methoxy-β-ketoesters. Coumarins are formed under dehydrated conditions, whereas benzofurans are formed in the presence of water. In the synthetic process of benzofurans, α-methoxy-β-ketoesters are converted into α-methoxyacetophenones, and the methoxy group is an important element in the intermolecular annulation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7b68d70853af1c058877bc1d9afbff8d https://doi.org/10.1055/s-0042-1751408 Zobrazit plný text záznamu