Pathogenesis of skin injury in immunodeficient rats

Autor: Levyts'kyĭ Ap, Hozhenko Ai, Shukhtin Vv
Rok vydání: 2013
Předmět:
Zdroj: Fiziolohichnyĭ zhurnal. 59:63-66
ISSN: 2522-9036
2522-9028
Popis: We investigated the skin condition in rats with immunodeficit induced by cyclophosphane. Cyclophosphane induced in the blood the development of two phases pathological process. The first leukopenic phase is mediated by the action ofcytostatics, and the second hyperleucocytic phase is induced by liver injury and splenomegalia. Dysbiosis and inflammation are developed in the skin, especially during the second phase.
Databáze: OpenAIRE