Pathogenesis of skin injury in immunodeficient rats
Autor: | Levyts'kyĭ Ap, Hozhenko Ai, Shukhtin Vv |
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Rok vydání: | 2013 |
Předmět: | |
Zdroj: | Fiziolohichnyĭ zhurnal. 59:63-66 |
ISSN: | 2522-9036 2522-9028 |
Popis: | We investigated the skin condition in rats with immunodeficit induced by cyclophosphane. Cyclophosphane induced in the blood the development of two phases pathological process. The first leukopenic phase is mediated by the action ofcytostatics, and the second hyperleucocytic phase is induced by liver injury and splenomegalia. Dysbiosis and inflammation are developed in the skin, especially during the second phase. |
Databáze: | OpenAIRE |
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