Comparative conformational analysis between an undecamer of DNA and its apurinic homologue

Autor:	J. Lhomme, Nathalie Berthet, Marie Louise Dheu-Andries, Christian Coulombeau, Laurence Fouilloux, Julian Garcia, C. Coulombeau, Pierre Vatton
Rok vydání:	1995
Předmět:	chemistry.chemical_compound chemistry Molecular model Stereochemistry Helix AP site A-DNA Physical and Theoretical Chemistry Condensed Matter Physics Biochemistry Molecular biology DNA Thymine
Zdroj:	Journal of Molecular Structure: THEOCHEM. 330:417-422
ISSN:	0166-1280
DOI:	10.1016/0166-1280(94)03870-q
Popis:	Molecular modeling of a DNA undecamer and a corresponding DNA apurinic undecamer (d(CGCACXCACGC) d(GCGTGTGTGCG), X = A or apurinic site) has been performed using the jumna program. Among the possible structures, several are slightly distorted and correctly fit the experimental data obtained from NMR measurements. In these structures, the thymine base that faces the apurinic site lies inside the double helix.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7b596a4c139b48d406ddedf3d479471f https://doi.org/10.1016/0166-1280(94)03870-q Zobrazit plný text záznamu