| Autor: |
A. E. Karpova, I. P. Shabalova, K. T. Kasoyan, L. G. Sozaeva, O. B. Shahova, A. V. Mironov, R. E. Kuznezov |
| Rok vydání: |
2022 |
| Zdroj: |
Medical alphabet. :28-32 |
| ISSN: |
2078-5631 |
| DOI: |
10.33667/2078-5631-2022-19-28-32 |
| Popis: |
Objective. Determination of the significance of cytological methods in the diagnosis of non-tumor lesions and endometrial tumors. Materials and Methods. 69 patients who underwent surgical treatment of hysterectomy or hysteroscopy with separate diagnostic scraping of the cervical mucosa and uterine cavity. The endometrial surface was scraped by Cytobrush. Part of the material was applied to a slide for conventional cytology (CC); the remaining material was placed into the vial for liquid-based cytology (LBC). The results were analyzed using SPSS Statistical Package (SPSS: An IBM Company). Results. Histological examination of biopsy material revealed endometrial hyperplasia without atypia (20), atypical hyperplasia (2) and adenocarcinoma (11). The sensitivity of CC and LBC for hyperplasia without atypia was estimated at 100 %, the specificity at 88 % and 94 %, respectively; the positive predictive value at 77 % and 87 %, respectively, and the negative predictive value at 100 %. The sensitivity of CC and LBC for atypical hyperplasia and adenocarcinoma was estimated at 100 %, specificity at 96 %; positive predictive value at 87 % and negative predictive value at 100 %. Conclusions. Exfoliative cytology of material from the uterine cavity can be used as an informative method for detecting endometrial cancer and hyperplasia. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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