Natural Pseudoguaianolides Prepared from Damsin
Autor: | Olov Sterner, A. Tito, M. Quiroz, Giovanna R. Almanza, Rodrigo Villagomez |
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Rok vydání: | 2015 |
Předmět: | |
Zdroj: | Chemistry of Natural Compounds. 51:675-680 |
ISSN: | 1573-8388 0009-3130 |
DOI: | 10.1007/s10600-015-1382-9 |
Popis: | Damsin (1) is a pseudoguaianolide sesquiterpene possessing potent biological activities, reported as a metabolite of several medicinal plants belonging to the genus Ambrosia together with related compounds. Starting from 1, which can be isolated in good amounts from Ambrosia arborescens, the five natural pseudoguaianolides ambrosin (2), isodamsin (3), 3 alpha-hydroxydamsin (4), 3 alpha-acetoxydamsin (5), and 11 beta,13-dihydrodamsin (8) were prepared by regio- and stereo-selective synthetic modifications. |
Databáze: | OpenAIRE |
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