Natural Pseudoguaianolides Prepared from Damsin

Autor: Olov Sterner, A. Tito, M. Quiroz, Giovanna R. Almanza, Rodrigo Villagomez
Rok vydání: 2015
Předmět:
Zdroj: Chemistry of Natural Compounds. 51:675-680
ISSN: 1573-8388
0009-3130
Popis: Damsin (1) is a pseudoguaianolide sesquiterpene possessing potent biological activities, reported as a metabolite of several medicinal plants belonging to the genus Ambrosia together with related compounds. Starting from 1, which can be isolated in good amounts from Ambrosia arborescens, the five natural pseudoguaianolides ambrosin (2), isodamsin (3), 3 alpha-hydroxydamsin (4), 3 alpha-acetoxydamsin (5), and 11 beta,13-dihydrodamsin (8) were prepared by regio- and stereo-selective synthetic modifications.
Databáze: OpenAIRE