Efficient Gas-to-Liquid Partition Using Gas-Flow Channels for Cell-Based Gaseous Odorant Detection
| Autor: | Norihisa Miki, Takuma Nakane, Shoji Takeuchi, Toshihisa Osaki, Hisatoshi Mimura |
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| Rok vydání: | 2021 |
| Předmět: |
inorganic chemicals
Aqueous solution Materials science Quantitative Biology::Neurons and Cognition Physics::Instrumentation and Detectors Mixing (process engineering) complex mixtures respiratory tract diseases Physics::Fluid Dynamics Gas to liquids Transducer Chemical engineering Shear stress Partition (number theory) Solubility Selectivity Astrophysics::Galaxy Astrophysics |
| Zdroj: | 2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers). |
| DOI: | 10.1109/transducers50396.2021.9495472 |
| Popis: | Cell-based sensors using olfactory receptors have attracted attention because of their high sensitivity and selectivity. A challenge is efficient partition of gaseous samples to the aqueous solution where the cell-based sensors reside. In this paper, we developed a device with a gas-flow channel, which allowed inflow of gaseous odorants over a well filled with aqueous solution. We considered that shear stress induced by the gas-flow at the gas-liquid interface initiate convectional mixing inside liquid and in turn, promotes partitioning of gaseous odorants into the solution. Solubility of a gaseous odorant was experimentally found to increase with the mixing strength. We further demonstrated efficient detection of a gaseous odorant using the sensor cells with the developed gas-flow device. |
| Databáze: | OpenAIRE |
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