Anti-Inflammatory Effects of Garlic Consumption and Regular Exercise in Sedentary Overweight Individuals
| Autor: | Farhad Gholami, Naser Amanollahi, Jabar Bashiri |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
GARLIC POWDER medicine.medical_specialty business.industry food and beverages 030209 endocrinology & metabolism Overweight Placebo food.food 03 medical and health sciences 030104 developmental biology 0302 clinical medicine food Statistical significance Internal medicine Post-hoc analysis Heart rate Medicine Analysis of variance medicine.symptom business Sedentary lifestyle |
| Zdroj: | Hormozgan Medical Journal. 24:e103143 |
| ISSN: | 2423-3536 2423-3528 |
| DOI: | 10.5812/hmj.103143 |
| Popis: | Background: A sedentary lifestyle can result in chronic inflammation, which is a risk factor for Cardiovascular Disease (CVD). Lifestyle modifications, including physical activity and herbal supplements, may have health benefits. Objectives: The present study aimed to investigate the effect of regular exercise and garlic consumption on some inflammatory biomarkers in sedentary overweight individuals. Methods: Forty-four sedentary overweight male participants (20 - 30 years) were randomized to the following groups: Exercise + garlic (ES), exercise + placebo (E), garlic (G), and placebo (P). The training protocol included 20 - 45 minutes of walking/running at 60 to 75% of the maximum heart rate, three sessions per week for eight weeks. Participants consumed two capsules containing 500 milligrams of garlic powder or placebo (starch) per day. Before and 48 h after the exercise intervention and supplement administration, blood samples were collected to assess the hs-CRP and TNF-α serum levels. One-way ANOVA and Tukey’s post hoc tests were used to analyze the data at a significance level of P < 0.05. Results: A significant difference was observed between the groups regarding the hs-CRP and TNF-α levels after the experimental period (P < 0.05). There was a significant difference between EG and placebo groups (P < 0.05). Conclusions: Based on the findings, garlic consumption, along with exercise training could exert anti-inflammatory properties in overweight subjects. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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