Cognitive profile in anti-NMDAR encephalitis: Neuropsychological evaluation, rehabilitation, and evolution. A case report
| Autor: | Nuria Montoro-Membila, Angel Gómez-Camello, Inmaculada Villegas-Rodríguez, Mónica Triviño-Mosquera |
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| Rok vydání: | 2021 |
| Předmět: |
050103 clinical psychology
medicine.medical_specialty Rehabilitation business.industry medicine.medical_treatment 05 social sciences Neuropsychology Cognition Anti-NMDAR Encephalitis 03 medical and health sciences 0302 clinical medicine Physical medicine and rehabilitation medicine 0501 psychology and cognitive sciences business 030217 neurology & neurosurgery |
| Zdroj: | Neuropsychologie clinique et appliquée. 4 |
| ISSN: | 2561-262X 2561-2611 |
| Popis: | Encephalitis associated with antibodies against the N-methyl-D-aspartate receptor (i.e., anti-NMDAR encephalitis) is an immune-mediated disorder mainly affecting girls and young women with ovarian teratoma. The clinical picture of the disease progresses from headaches and seizures, psychopathological symptoms (i.e., anxiety, psychosis, or hyperreligiosity), and neuropsychological deficits (i.e., memory, attention, and language disintegration) into a state of agitation, catatonia, dysautonomia (i.e., abnormal movements due to inappropriate muscular activity) and facial dyskinesia. Reports of the neuropsychological profile and evolution, as well as the neuropsychological rehabilitation in anti-NMDAR encephalitis in the literature are scarce. We present the case of a 21-year-old woman diagnosed with anti-NMDAR encephalitis and we describe the different neuropsychological evaluation tests performed before and after neuropsychological rehabilitation during the acute period. A profile of fronto-subcortical neuropsychological damage was observed, with executive functions and emotional regulation affected. |
| Databáze: | OpenAIRE |
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