Susceptibility of Salmonella typhi and Brucella melitensis to the New Fluoroquinolone Rufloxacin (MF 934)
| Autor: | H. Saldin, A. Ayub, S.M. Qadri, Y. Ueno |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Pharmacology
Salmonella biology Rufloxacin General Medicine Brucella Antimicrobial biology.organism_classification medicine.disease_cause Salmonella typhi Virology Microbiology chemistry.chemical_compound Minimum inhibitory concentration Infectious Diseases Oncology chemistry Drug Discovery medicine Pharmacology (medical) Antibacterial agent Brucella melitensis |
| Zdroj: | Chemotherapy. 39:311-314 |
| ISSN: | 1421-9794 0009-3157 |
| DOI: | 10.1159/000239142 |
| Popis: | The antimicrobial activity of the new fluoroquinolone rufloxacin (MF 934) was evaluated by a standardized agar dilution method against recent clinical isolates of Salmonella typhi (67 strains) and Brucella melitensis (108 isolates). The results were compared with 5 other commercially available or investigational fluoroquinolones. All the isolates of S. typhi were inhibited by 1.0 mg/l of rufloxacin as compared to 4-8 mg/l for B. melitensis. Minimum inhibitory concentrations of rufloxacin against both S. typhi and B. melitensis were 4-16 times higher than those of other fluoroquinolones. |
| Databáze: | OpenAIRE |
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