Structure-function analysis of the radioprotective and antioxidant activity of flavonoids

Autor: É. P. Kemertelidze, V. G. Tsitsishvili, T. G. Sagareishvili, M. D. Alaniya
Rok vydání: 2000
Předmět:
Zdroj: Chemistry of Natural Compounds. 36:54-59
ISSN: 1573-8388
0009-3130
DOI: 10.1007/bf02234904
Popis: The recombination kinetics of a series of flavonoids with stable DPPH radicals are studied. Flavonols are the most reactive. Polarization of the carbonyl in flavones reduces the reactivity. Substitution on C-7 and the B ring has practically no effect on the reactivity. Glycosylation of C-3 reduces the reactivity if the sugar can form two intramolecular H-bonds. The reactivity of the flavonoid phenol hydroxyls, with the exception of the hydroxyl on C-5, is proportional to their number. The most promising antioxidants are lespedin, kaempferitrin, kaempferol, kaempferol-7-rhamnoside, kaempferol-3-robinobioside, and robinin.
Databáze: OpenAIRE