Structure-function analysis of the radioprotective and antioxidant activity of flavonoids
Autor: | É. P. Kemertelidze, V. G. Tsitsishvili, T. G. Sagareishvili, M. D. Alaniya |
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Rok vydání: | 2000 |
Předmět: | |
Zdroj: | Chemistry of Natural Compounds. 36:54-59 |
ISSN: | 1573-8388 0009-3130 |
DOI: | 10.1007/bf02234904 |
Popis: | The recombination kinetics of a series of flavonoids with stable DPPH radicals are studied. Flavonols are the most reactive. Polarization of the carbonyl in flavones reduces the reactivity. Substitution on C-7 and the B ring has practically no effect on the reactivity. Glycosylation of C-3 reduces the reactivity if the sugar can form two intramolecular H-bonds. The reactivity of the flavonoid phenol hydroxyls, with the exception of the hydroxyl on C-5, is proportional to their number. The most promising antioxidants are lespedin, kaempferitrin, kaempferol, kaempferol-7-rhamnoside, kaempferol-3-robinobioside, and robinin. |
Databáze: | OpenAIRE |
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