From rose petal to bone scaffolds: Using nature to fabricate osteon-like scaffolds for bone tissue engineering applications
| Autor: | Shima Mahtabian, Fariborz Tavangarian, Seyed Mehdi Mirhadi |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
010302 applied physics
Pore diameter Materials science Biocompatibility Process Chemistry and Technology fungi Haversian canal 02 engineering and technology Rose (topology) 021001 nanoscience & nanotechnology 01 natural sciences Bone tissue engineering Surfaces Coatings and Films Electronic Optical and Magnetic Materials medicine.anatomical_structure Osteon 0103 physical sciences Materials Chemistry Ceramics and Composites medicine Petal Lamellar structure 0210 nano-technology Biomedical engineering |
| Zdroj: | Ceramics International. 47:21633-21641 |
| ISSN: | 0272-8842 |
| DOI: | 10.1016/j.ceramint.2021.04.176 |
| Popis: | In this study, rose petal was used to fabricate osteon-like scaffolds for bone tissue engineering applications. Rose petal was coupled with nanocrystalline forsterite colloid to mimic the lamellar structure of porous osteons. The microstructures on the surface of the petals were utilized as template for pores and lacuna spaces which are suitable for cell attachment. On the other hand, rolling the petals allowed us to form the osteon structure with haversian canal and lacuna spaces on the body of the samples. After trying different temperatures, the results showed that samples annealed at 1100 °C closely mimicked the lacuna spaces, haversian canal, and lamellar structures of osteons. These scaffolds had the pore diameter in the range of about 13–20 μm and presented good bioactivity and biocompatibility. It was found that red rose petal is a good candidate to be used as a template for designing scaffolds for bone tissue engineering applications. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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