Popis: |
Infectious, inflammatory, and reactive lesions involving the CNS, which form an increasing part of the diagnostic workload in many neuropathology laboratories, are often more challenging than neoplastic lesions when evaluated by frozen section. In this compromising situation, the cytologic method can be the best ally, because the characteristic features of inflammatory cells and macrophages, often obscured in frozen sections, are nicely preserved in smears. This chapter reviews the cytomorphology and differential diagnosis of CNS acute inflammatory cell-rich lesions, CNS perivascular chronic inflammatory cell-rich lesions, CNS epithelioid-cell-rich (granulomatous) lesions, CNS macrophage-rich lesions, and CNS inflammatory/infectious lesions in AIDS patients. |