Chemoenzymatic synthesis of Fmoc-protected (2S,3S)-2-hydroxy-3-amino acids and their application in the synthesis of an α-hydroxylated β-hexapeptide
Autor: | Gijs A. van der Marel, Alessia Amore, Arne van der Gen, Michael van der Hoeven, Reynier A. Tromp, Johannes Brussee, Mark Overhand |
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Rok vydání: | 2001 |
Předmět: | |
Zdroj: | Tetrahedron: Asymmetry. 12:1109-1112 |
ISSN: | 0957-4166 |
Popis: | A chemoenzymatic and stereoselective synthesis of Fmoc-protected (2 S ,3 S )-2-hydroxy-3-amino acids from 2-furaldehyde is described as well as their application, without prior hydroxyl protection, in the solid-phase synthesis of a novel completely α-hydroxylated β-hexapeptide. |
Databáze: | OpenAIRE |
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