Apoplectic leiomyomas: does ethnicity make a difference? a clinicopathologic study
| Autor: | Stewart F. Cramer, Debra S. Heller, Bradley M. Turner, Fattaneh A. Tavassoli |
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| Rok vydání: | 2021 |
| Předmět: |
Gynecology
medicine.medical_specialty Uterine leiomyoma business.industry Cell Biology General Medicine musculoskeletal system medicine.disease female genital diseases and pregnancy complications Pathology and Forensic Medicine body regions surgical procedures operative Leiomyoma medicine Hormonal therapy Nuclear atypia business neoplasms Molecular Biology Hormone Apoplectic leiomyoma |
| Zdroj: | Virchows Archiv. 480:645-654 |
| ISSN: | 1432-2307 0945-6317 |
| DOI: | 10.1007/s00428-021-03225-z |
| Popis: | Apoplectic leiomyomas—benign uterine leiomyomas with morphologic changes including hemorrhage, hypercellularity, mitotic activity, nuclear atypia, and even necrosis—can be difficult to distinguish from uterine leiomyosarcomas. Apoplectic leiomyomas have been associated with hormonal therapy; however, the relationship between apoplectic leiomyomas, hormones, and ethnicity has not received much attention in the literature. We evaluated the relationship of hormonal therapy and ethnicity in 869 women with uterine leiomyomas, 136 of which qualified as apoplectic leiomyomas. Apoplectic leiomyomas were observed in 23.3% (49/210) of women exposed to hormonal therapy compared to 13.2% (87/659) of women not exposed to hormonal therapy (p 45 years of age (p |
| Databáze: | OpenAIRE |
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