Vitamin D Levels, Physical and Biochemical Characteristicsof South East Asian Patients with Osteoporotic Hip Fractures
| Autor: | Seo Kiat Goh, Alvin Choong Meng Ng, Rong Fang Zhang, Manju Chandran, Tet Sen Howe, Joyce Suang Bee Koh, HH Li |
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| Rok vydání: | 2012 |
| Předmět: |
Bone mineral
education.field_of_study Hip fracture medicine.medical_specialty business.industry Endocrinology Diabetes and Metabolism Population Renal function musculoskeletal system medicine.disease Logistic regression vitamin D deficiency Surgery Endocrinology medicine.anatomical_structure Vitamin D and neurology Medicine business education Femoral neck |
| Zdroj: | Journal of the ASEAN Federation of Endocrine Societies. 27:185-190 |
| ISSN: | 2308-118X 0857-1074 |
| Popis: | Objective. Limited information exists on the physical characteristics, bone mineral density (BMD), 25-hydroxyvitamin D [25(OH)D] levels and other biochemical parameters in patients with hip fractures in Asia. We aimed to explore whether these parameters differ between trochanteric and femoral neck (cervical) hip fractures in Singaporean patients. Methodology. 275 patients with osteoporotic hip fractures were evaluated. Multivariate regression models were used to investigate the relationship between physical characteristics, biochemical parameters, renal function, BMD and type of hip fracture. Results. The mean 25(OH)D level noted was 20.4 (8.1) ng/mL. Fifty percent of patients had levels less than 20 ng/mL. Patients with trochanteric fractures were heavier than those with cervical fractures ( p =0.021). Logistic regression analysis showed that males were more likely to have trochanteric fractures (OR=1.79, 95% CI 1.03-3.11), and females with trochanteric fractures were older than those with cervical fractures (OR=0.97, 95% CI 0.94-1.00). Conclusion. Vitamin D deficiency was prevalent in half of our population of hip fracture patients. Trochanteric fractures were more common than cervical fractures in men and in older women. In contrast to findings noted in Caucasian populations, neither BMD nor other bone metabolic parameters examined were associated with the preferential occurrence of one type of osteoporotic hip fracture over the other. |
| Databáze: | OpenAIRE |
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