Clinical laboratory assessment of the abuse liability of an electronic cigarette

Autor:	Andrea R. Vansickel, Michael F. Weaver, Thomas Eissenberg
Rok vydání:	2012
Předmět:	medicine.medical_specialty Subjective effects business.industry media_common.quotation_subject Medicine (miscellaneous) Abstinence law.invention Nicotine Psychiatry and Mental health stomatognathic system law Internal medicine Electronic Nicotine Delivery Device Abuse liability Medicine Young adult Tobacco Use Cessation Products business Social psychology Electronic cigarette medicine.drug media_common
Zdroj:	Addiction. 107:1493-1500
ISSN:	0965-2140
Popis:	Aims To provide an initial abuse liability assessment of an electronic cigarette (EC) in current tobacco cigarette smokers. Design The first of four within-subject sessions was an EC sampling session that involved six, 10-puff bouts (30 seconds inter-puff interval), each bout separated by 30 minutes. In the remaining three sessions participants made choices between 10 EC puffs and varying amounts of money, 10 EC puffs and a varying number of own brand cigarette (OB) puffs, or 10 OB puffs and varying amounts of money using the multiple-choice procedure (MCP). The MCP was completed six times at 30-minute intervals, and one choice was reinforced randomly at each trial. Setting Clinical laboratory. Participants Twenty current tobacco cigarette smokers. Measurements Sampling session outcome measures included plasma nicotine, cardiovascular response and subjective effects. Choice session outcome was the cross-over value on the MCP. Findings EC use resulted in significant nicotine delivery, tobacco abstinence symptom suppression and increased product acceptability ratings. On the MCP, participants chose to receive 10 EC puffs over an average of $1.06 or three OB puffs and chose 10 OB puffs over an average of $1.50 (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7a8076c932247cd8fdd2bd66af9f16fd https://doi.org/10.1111/j.1360-0443.2012.03791.x Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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