Gram positive uropathogens and their antibiogram: Data analysis at a tertiary care hospital in Karnataka
| Autor: | Trupti B. Naik, Amruthkishan K. Upadhya, Vijaykumar Mane, J. Lavanya |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
biology business.industry medicine.drug_class Gram-positive bacteria Antibiotics biology.organism_classification chemistry.chemical_compound Antibiotic resistance chemistry Nitrofurantoin Internal medicine Ampicillin Linezolid medicine Vancomycin Gentamicin business medicine.drug |
| Zdroj: | Indian Journal of Microbiology Research. 5:71-75 |
| ISSN: | 2394-5478 2394-546X |
| DOI: | 10.18231/2394-5478.2018.0014 |
| Popis: | Introduction: Urinary tract infections (UTI) are one of the most common infections encountered in clinical settings, being amenable to easy diagnosis with established laboratory methods. However, in recent years, antibiotic resistance has become a major public health problem worldwide owing to the extensive and inappropriate use of antimicrobial agents. Objectives: 1. To determine the various Gram positive isolates causing urinary tract infections. 2. To determine the antibiotic susceptibility pattern of Gram positive cocci. Material and Methods: A cross sectional study was conducted at a private tertiary care hospital in Shivamogga district of Karnataka, using secondary data of Gram positive bacteria isolated from urine samples maintained in the Microbiology laboratory registers for a period of 1 year from January 2016 to December 2016. Standard protocols were followed for bacteria isolation, identification and to assess their antibiotic susceptibility. Statistical analysis was done using MS office Excel 2010. Results: Of the total 1254 urine specimens, 466 (37.16%) revealed positive cultures. Out of the 512 isolates from positive cultures, 196 (38.28%) were Gram positive bacteria. The predominant isolates i.e. 86 (43.87%) belonged to Enterococcus species. All the isolates were susceptible to Linezolid and Vancomycin. Majority i.e. 184 (93.87%) were sensitive to nitrofurantoin followed by gentamicin 146 (74.48%) and majority showed resistance to ampicillin i.e.126 (64.28%). Conclusion: The rise in the resistance among uropathogens alerts us against indiscriminate use of antibiotics, indicating the need to establish antibiotic policies along with stringent measures to ensure effectiveness of the same. Keywords: Antibiogram, Gram positive isolates, Urinary tract infection. |
| Databáze: | OpenAIRE |
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