AB1258 THE PREDICTED VERSUS MEASURED RESPIRATORY PRESSURES, PULMONARY FUNCTIONS, CARDIOPULMONARY FITNESS PARAMETERS IN CHILDREN WITH JUVENILE IDIOPATHIC ARTHRITIS

Autor: D. C. Saraç, D. Bayraktar, D. Ozer Kaya, O. Altug-Gucenmez, D. Oskay
Rok vydání: 2022
Předmět:
Zdroj: Annals of the Rheumatic Diseases. 81:1739.1-1739
ISSN: 1468-2060
0003-4967
Popis: BackgroundAlthough musculoskeletal system-related symptoms are the most common problems in children with Juvenile Idiopathic Arthritis (JIA), cardiac and pulmonary manifestations are observed in more than half of these children. However, the available research on the extent of cardiorespiratory involvement is very limited [1].ObjectivesThe aim of this study was to compare the predicted respiratory pressures, pulmonary functions, cardiopulmonary exercise test (CPET) values to objectively measured ones in children with JIA.MethodsTwenty-two children with JIA (mean age: 15.5±2.3, 14 male) who were under biological agents for at least three months were included in the study. Maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP), and pulmonary functions were measured by using a portable automated testing device (Cosmed Pony FX Desktop Spirometer, USA). Cardiorespiratory fitness parameters were measured with the Quark CPET Treadmill System (COSMED, Rome, Italy). The values calculated by the softwares of the Cosmed Pony FX Desktop Spirometer and Quark CPET Treadmill System according to the healthy children’s normative data were used as predictive values.ResultsWithin-group analyses demonstrated statistically significant differences between all measured and predicted parameters (pTable 1.The comparison of predicted versus measured respiratory pressures, pulmonary functions, cardiopulmonary fitness parametersMeasuredPredictedp(Mean±SD)(Mean±SD)FVC (l)3.82±0.924.20±1.04FEV1(l)3.31±0.803.59±0.860.004*FEV1/FVC (%)86.13±7.7483.91±0.410.179MIP (cmH2O)101.90±37.45104.31±21.920.686MEP (cmH2O)95.13±47.84134.36±30.22VO2max(ml/kg/min)2109.83±732.953159.94±745.87METs (ml/kg/min)9.71±2.18014.88±2.39HR (bpm)187.88±20.28205.0±2.370.02*VO2/HR (ratio)11.2015.42±3.75*:pFVC: Forced vital capacity, FEV1: Forced expiratory volume, FEV1/FVC: Forced expiration volume/forced vital capacity, VO2max: Maximum oxygen consumption, ml: milliliters, kg: kilograms, min: minute, METs: Metabolic equivalent HR: Heart rate, bpm: beats per minute, VO2/HR: Oxygen consumption/heart rate.ConclusionThe present study’s findings indicate that the respiratory pressures, pulmonary functions, and cardiopulmonary fitness parameters of the children with JIA are diminished compared to predicted values.References[1]Alkady EA, Helmy HA, Mohamed-Hussein AA (2012) Assessment of cardiac and pulmonary function in children with juvenile idiopathic arthritis. Rheumatol Int 32(1):39-46. https://doi.org/10.1007/s00296-010-1548-5Disclosure of InterestsNone declared
Databáze: OpenAIRE
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