Use of fluorinated palladium sources for efficient Pd-catalysed coupling reactions in supercritical carbon dioxide

Autor:	Najam Shezad, Anthony A. Clifford, R. Scott Oakes, Christopher M. Rayner
Rok vydání:	1999
Předmět:	chemistry.chemical_compound Supercritical carbon dioxide chemistry Organic Chemistry Drug Discovery Polymer chemistry Inorganic chemistry chemistry.chemical_element Biochemistry Coupling reaction Phosphine Catalysis Palladium
Zdroj:	Tetrahedron Letters. 40:2221-2224
ISSN:	0040-4039
Popis:	Commercially available palladium sources [Pd(OCOCF 3 ) 2 and Pd(F 6 -acac) 2 ] containing fluorinated ligands are superior to non-fluorinated sources [Pd(OCOCH 3 ) 2 and Pd 2 (dba) 3 ] for carrying out a variety of palladium catalysed coupling reactions in supercritical carbon dioxide. Significantly reduced temperatures and catalyst loadings are possible, and also the range of phosphine ligands which can be used is increased, including those that are often considered to be poor ligands for coupling reactions under conventional conditions (PCy 3 , PBu 3 ).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7a35ad188c02130221ffc858fa54e1e7 https://doi.org/10.1016/s0040-4039(99)00176-8 Zobrazit plný text záznamu Full Text from ScienceDirect