Optimal Lead Selection for Evaluation Ventricular Premature Beats Using Machine Learning Approach
| Autor: | Drago Torkar, Pedro David Arini |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
business.industry
Rabbit heart 030204 cardiovascular system & hematology Machine learning computer.software_genre Both ventricles 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Ventricle medicine Repolarization Ventricular premature beats Artificial intelligence Lead (electronics) business computer Electrode placement 030217 neurology & neurosurgery Site of origin |
| Zdroj: | Biomedical Engineering Systems and Technologies ISBN: 9783319547169 BIOSTEC (Selected Papers) |
| DOI: | 10.1007/978-3-319-54717-6_11 |
| Popis: | Repolarization heterogeneity (RH) has been shown to increase with ventricular premature beats (VPBs). Moreover, several differences between left ventricle (Lv) and right ventricle (Rv), such as fibrillation threshold and anatomic properties have been presented. Nevertheless, few results exist regarding the influence of the origin site of VPBs on modulation of ventricular RH, as well as the optimal electrode location to assess the origin of VPBs. We studied electrocardiographic indices as a function of the coupling interval and the site of VPBs, in an isolated rabbit heart preparation (n = 18) using ECG multi-lead (5 rows \(\times \) 8 columns) system. In both ventricles, results have shown significant increases in ventricular depolarization duration. Also, we have observed that when the VPBs were applied to the Lv, a significant decrease of the total repolarization duration was detected, while in the Rv premature stimulation we have not found significant changes of total repolarization duration. Also, we compared twenty machine learning classification techniques with the aim to find the optimal electrode placement (row4–column4 to Lv stimulation and row5–column3 to Rv stimulation) and interpret the site of origin of VPBs. It was observed that the Random Forest classifier has shown the best performance among all the techniques studied. Finally, we found differences in the overall duration of repolarization associated to transmural RH. |
| Databáze: | OpenAIRE |
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