High-performance liquid chromatography of α-amino acid enantiomers on eremomycin-modified silica

Autor:	G. G. Vasiyarov, Pavel N. Nesterenko, M. A. Kuznetsov, S. M. Staroverov
Rok vydání:	2008
Předmět:	chemistry.chemical_classification Chromatography Elution Silica gel High-performance liquid chromatography Analytical Chemistry Amino acid Chiral column chromatography chemistry.chemical_compound Aglycone chemistry Organic chemistry Enantiomer Chiral derivatizing agent
Zdroj:	Journal of Analytical Chemistry. 63:57-64
ISSN:	1608-3199 1061-9348
DOI:	10.1134/s1061934808010115
Popis:	The chromatographic behavior of enantiomers of α-amino acids was studied on new chiral stationary phases based on silica gel with macrocyclic glycopeptide antibiotic eremomycin and its aglycone immobilized on the surface. The retention of adsorbates and enantioselectivity of their separation were studied as functions of the structure of the side group of α-amino acids, eluant pH, concentration of organic modifier in the eluant, and temperature. The mechanism of the chiral recognition of α-amino acid enantiomers is discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::79eaf0c3e4e6ed6746022c9927d44f55 https://doi.org/10.1134/s1061934808010115 Zobrazit plný text záznamu Plný text ve formátu PDF