Squamous Carcinoma of the Cervix in a 15-Year-Old with Congenital HIV: A Case Report
| Autor: | Melanie Evans, Ashli Lawson, Ellen E. Wilson, Jason Jarin |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Oncology
medicine.medical_specialty Congenital HIV 03 medical and health sciences Sexually active 0302 clinical medicine 030225 pediatrics Internal medicine Biopsy medicine Human papillomavirus Cervix Cervical cancer 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry HPV infection virus diseases Obstetrics and Gynecology General Medicine medicine.disease female genital diseases and pregnancy complications Squamous carcinoma medicine.anatomical_structure Pediatrics Perinatology and Child Health business |
| Zdroj: | Journal of Pediatric and Adolescent Gynecology. 34:234-237 |
| ISSN: | 1083-3188 |
| DOI: | 10.1016/j.jpag.2020.08.014 |
| Popis: | Background Human papillomavirus (HPV) is the most prevalent sexually transmitted infection (STI) worldwide. Immunocompetent hosts have intact defense mechanisms to prevent HPV infection, but immunocompromised patients are at higher risk for complications, including HPV-related cancers. Most of these cancers originate from high-risk HPV strains in sexually active patients. Case Here we present a case of an immunocompromised adolescent who developed cervical cancer despite no prior sexual activity and only ever having had low-risk type HPV on biopsy. Summary and Conclusions To our knowledge, this is the first case report of a cervical cancer arising from a low-risk HPV strain in an immunocompromised, non−sexually active adolescent. This case highlights the importance of preventive and screening mechanisms in immunocompromised populations, as they are have a higher probability of HPV-related complications, even in the absence of traditional risk factors. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect